Current Issue : January-March Volume : 2015 Issue Number : 1 Articles : 5 Articles
The objective of this study was to develop a gel of Putranjiva roxburghii for its anti-inflammatory activity. Topical delivery system of Putranjiva leaf gel was formulated using carbopol 940. The gel was evaluated for physicochemical parameters like physical appearance, pH, homogeneity and viscosity....
Terminalia arjuna bark is one of the key botanical ingredient used in the ayurvedic system of medicine. It has proven to be highly beneficial in the treatment of cardio-vascular disorders. Extracts of Terminalia arjuna bark is being used in several ayurvedic formulations as single ingredient or in combination with other herbs. Terminalia arjuna is known to contain several oleane derivatives out of which arjunolic acid is one of the key ingredient and used as an analytical marker for the standardisation of arjuna bark containing preparations. The evaluation of the stability of the sample is done by stability indicating assay. In the current study we have used arjunolic acid as a validated stability indicating assay for the determination of shelf life in arjuna caplets. We developed a stability indicating assay for Terminalia arjuna. Here we used HPTLC and HPLC methods to evaluate the stability of Terminalia arjuna. The HPTLC fingerprint serves as a reference to evaluate the authenticity of the herb used. The validation of the assay was found to be accurate (0.73 to 1.87 %RSD), precise (0.58 to 0.80 %RSD) and linear (R2 - 0.9999). The results were found to be accurate and reproducible. The arjuna caplets were found to be stable in accelerated conditions for 6 months....
Medicinal plants are of great value with in the field of treatment and cure of liver diseases. Herbal drugs have become progressively popular and their use is extensively distributed. Herbal drugs are more widely used than allopathic drugs as hepatoprotectives because they are inexpensive, have better cultural acceptability, better compatibility, with the human body and minimal side effects. Clinically it was proven that herbal drugs have profound utility in the treating liver ailments. An oversized variety of plants are claimed to own hepatoprotective activity. Nearly 169 phytoconstituents from 108 plants have been reported as having liver protecting activity. The present review discuss on the different types of herbal (natural) drugs utilized in the liver treatment....
Aim of the present study was to perform preliminary phytochemical screening and evaluate the anti bacterial activity for three extracts ethanolic, petroleum ether and aqueous of Adhatoda vesica belonging to family Acanthaceae. Adhatoda vesica is an important herb in the Indian system of ayurvedic medicine. It has been traditionally used to treat cough, whooping cough, cold and clung phlegm in mouth, throat, chest or breast. It is also effective against Tuberculosis, fever, leukaemia and skin diseases. Study was conducted using aqueous, pet. Ether and ethanolic extract leaves. A preliminary phytochemical screening was also performed for qualitative determination of the phytoconstituents. Antibacterial assay was carried out using different strains of bacteria like Escherichia coli (MTCC No.40), Staphylococcus aureus (MTCC No.87), Proteus vulgaris (MTCC No.742), Pseudomonas aeruginosa (MTCC No.424), Bacillus subtilis (MTCC No.441), Staphylococcus epidermidis (MTCC No.9041) and Micrococcus luteus (MTCC No.106), using cup plate method. Phytochemical screening indicated the presence of phenols, tannins, alkaloids, anthraquinones, saponins, flavonoids, amino acids and reducing sugars. From anti microbial assay was found that ethanolic extract was effective against all the bacterial strains, where as mixed effect observed in remaining two extracts....
Mnesithea granularis is a plant of Indian origin having tremendous therapeutic potential but is not fully utilized. It is a highly valued plant and has an impressive range of medicinal uses. The present study primarily aims to carry out a preliminary phytochemical screening of different extracts and fractions of Mnesithea granularis and to perform thin layer chromatography (TLC) profiling of hydroalcoholic extract and different fractions of hydroalcoholic extract of Mnesithea granularis. Phytochemical analysis was performed by various qualitative methods and TLC profiling was carried out using various solvent systems of varying polarity. Qualitative phytochemical analysis reflects the presence of carbohydrates, proteins, amino acids, anthracene derivatives, cardiac glycosides, flavonoids, tannins, saponins and terpenoids. TLC profiling of Mnesithea granularis was constituted different coloured phytochemical compounds with different Rf values. The present study provides evidence that solvent extract of Mnesithea granularis contains medicinally important bioactive compounds and this justifies the use of plant as traditional medicine for treatment of various diseases....
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